Similar to the host of symptoms listed above, proponents of pyroluria disease suggest it is associated with numerous other health conditions.
But all are unclear about whether or not pyroluria causes these conditions or if these conditions cause pyroluria (the chicken or the egg conundrum).
I don’t think there’s any question that pyrroles exist. The symptoms people experience are also likely real, but whether or not these symptoms are a cause and effect result of excess pyrroles in the urine is yet to be proven.
Some common questions about this condition include “is pyroluria real? Back in the 1960s, during the heyday of the psychedelic revolution, the originators of the pyroluria hypothesis (Hoffer and colleagues) figured that since the effects of LSD were similar to those with schizophrenia that perhaps they could derive some insights from “trippers.”They looked for biomarkers in the urine of subjects on LSD, one of which was identified as kyrptopyrrole.
They assumed that since kryptopyrrole is present in the urine of those taking LSD and those with schizophrenia, then it must be a factor in the development of a host of other mental and physical disturbances (mentioned below).
Pyroluria promoters claim that it is a genetically-determined chemical imbalance associated with haemoglobin synthesis (the molecule that carries oxygen in your blood).
People with the condition produce too much kryptopyrrole as a byproduct of haemoglobin production and it is excreted in the urine.
Proponents suggest that this excess kryptopyrrole binds vitamin B6 and zinc, renders them unavailable for their usual biological roles, and then excretes them through the urine as pyrroles.
Accordingly, sufferers may exhibit signs of vitamin B6 and zinc deficiency which could possibly account for symptoms like depression, anxiety, mood swings, nervousness, and a litany of other suggested ills.
Aside from those listed above, I’ve highlighted a number of other symptoms I found listed across a variety of websites.
However, I think it’s important to exercise caution when “diagnosing” yourself given that these symptoms are all quite vague, ambiguous, and nondescript, and could be attributed to virtually any serious illness.
The cultural forces that have made the push for affordable and accessible child care part of the national agenda, even for previous working-mom-phobes like Donald Trump, have failed to reach most institutions of higher learning.